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SHAHEED ZIAUR RAHMAN MEDICAL COLLEGE

An Open Access, Double-Blind Peer-Reviewed Journal

ISSN: 1607-5854

Pattern and Outcome of Acute Poisoning Cases Admitted at a Tertiary Care Hospital, Bangladesh

1*1. Dr. Md. Ahsan Habib, Assistant Professor, Department of Medicine, Shaheed Ziaur Rahman Medical College, Bogura

2Professor Dr. Md. Abdus Salam, Head of the Department of Medicine, Shaheed Ziaur Rahman Medical College, Bogura.

3Dr. Md. Kamal Hossain, Associate Professor, Department of Medicine, Shaheed Ziaur Rahman Medical College.

4Dr. Md. Mamunur Rashid, Associate Professor, Department of Medicine, Shaheed Ziaur Rahman Medical College.

5Dr. Md. Kamruzzaman, Assistant Professor, Non-Invasive Cardiology, National Institute of Cardio Vascular Diseases, Dhaka

6Dr. Suraya Sarmin, Assistant Professor, Institute of Nuclear Medicine & Allied Science, Bogura.

*Corresponding author: drtusar58@gmail.com

Abstract

Background: Acute poisoning is of about 7.1% of hospital admissions in Bangladesh. According to the WHO, 99% of the fatal poisoning cases occurred in developing countries. The pattern of poisoning & socio demographic parameters varies in times, from one country to another, even among different regions of a country. Objective of this study was to study the clinical profile of patient presenting with acute poisoning; and, to study the outcome of the patient presenting with poisoning.
Methods: This retrospective observational hospital record based study carried out at the Department of Medicine, Shaheed Ziaur Rahman Medical College Hospital, Bogura from 1st March, 2025 to 31th August, 2025. Total 781 cases were included by purposive sampling technique.  All the recorded data of poisoning cases age more than 12 years admitted in the medicine units, included in this study. Snake bite, food poisoning, and electrocution, near drowning, drug reaction were excluded from the study.
Results: Within the total 781 patients of both genders were studied, males were slightly more than the females and the male: female ratio was 1.11: 1. Among 781 cases, majority were in the age ranged from 12-30 years, few from 31-40 years and least > 40 years. By occupation, students were most predominantly affected followed by housewife, farmer, day laborers, service holders, unemployed, and business workers. Most participants resided in rural areas, while smaller proportions were from semi-urban and urban areas. Regarding education 2/3rd had secondary & higher secondary education, rest had primary and graduate degree or higher. Most common mode of poisoning was OPC, followed by benzodiazepine, aluminium phosphide, mixed/unknown/others, herpic , parquet , drug/alcohol overdose, insecticide , other household chemical, rat killer, insect bite, other agrochemicals, others rodenticides . Males more often had OPC, benzodiazepines, parquet, and insect bites, whereas females predominated in herpic, drug/alcohol overdose, other household chemicals, and rat killer. 93.3% of patients survived while 6.7% resulted in death. Death was more frequent among males compared to females. Survival was highest in younger groups. Maximum patient died due aluminium phosphide poisoning followed by OPC & others.
Conclusion: The trends of poisoning vary at different parts of the world and may vary even in different regions of the country. In the present study, females had a higher recovery rate compared to males and deaths were more frequent among males. The most common mode of poisoning was OPC but the most death had occurred due to aluminium phosphide poisoning. Overall, comprehensive strategies focusing on prevention, regulation, and timely treatment are vital to reduce the incidence and improve the outcomes and mitigate burden of acute poisoning cases in Bangladesh.

Keywords

Poisoning Death rate Aluminium Phosphide OPC Paraquat Insecticide Rat-killer.

1. INTRODUCTION

Acute poisoning is common, accounting for about 1% of hospital admissions in the UK1.
Common important substances involving poisoning in UK are1: analgesics: Paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs), antidepressants: selective serotonin re-uptake inhibitors (SSRIs), serotonin nor epinephrine re-uptake inhibitors, tricyclic antidepressants (TCAs) and lithium, cardiovascular agents: β-blockers, calcium channel blockers and cardiac glycosides, Drugs of misuse: anti-depressants, opiates, benzodiazepines, stimulants and entactogens (e.g. amphetamines, MDMA, mephedrone, cocaine), hallucinogens e.g. cannabis, synthetic cannabinoid receptor agonists), carbon monoxide, alcohol.
But in South and South-east Asia, common or otherwise important substances involved are: organophosphorus and carbamate insecticides, aluminium and zinc phosphide, paraquat, oleander, corrosives, snake and insect venoms1.
Poisoning is a major cause of death in young adults; most deaths occur before patients reach medical attention. Accidental poisoning is also common, especially in children and older people. Criminal poisoning may also occur, including drug-facilitated robbery or sexual assault.
In low- and middle-income countries, the frequency of self-harm is more difficult to estimate. Because of their widespread availability and use, household and agricultural products, such as pesticides and herbicides, are common sources of poisoning and have a much higher case fatality. In China and South-east Asia, pesticides account for about 300,000 suicides each year.
Snake bite and other forms of envenomation are also important causes of morbidity and mortality internationally. According to the World Health Organization, 99% of the fatal poisoning cases occurred in developing countries2.
In our country it causes around 3,000,000 episodes and around 2000 death per year. It consumes not only the valuable health service resources but also causes considerable morbidity and mortality3.
Poisoning is a serious threat in Bangladesh as it comprises around 44% of all deaths among adult females and around 8 to 10% of overall mortality in medical wards of tertiary healthcare settings4.
Common types of poisoning in this country are organophosphorus poisoning, poisoning with unknown substances especially in commuter (travel-related) poisoning; poisoning with sedatives, aluminium phosphide, corrosive agents, rodenticides, kerosene/petrol and alcohol, and snakebite4,5.
The pattern of poisoning as well as their sociodemographic parameters varies in times and, from one country to another, even among different regions of a country.
This study was carried out to describe the sociodemographic profile, pattern of poisoning and outcome in a tertiary level hospital in Bangladesh.
Objectives of this study was to study the clinical profile of patient presenting with acute poisoning; and, to study the outcome of the patient presenting with poisoning.

Published: January 9, 2026

DOI: 324654-5646

ISSN: 1607-5854